*= Corresponding author when not last author
293 Van Nguyen TH, Tsapis N, Benrabah L, Gouilleux B, Baltaze JP, Domenichini S, Fattal E, Moine L. Poly(malic acid) Nanoconjugates of Pyrazinoic Acid for Lung Delivery in the Treatment of Tuberculosis. Bioconjugate Chemistry 35 (10), 1532-1542, 2024 – https://doi.org/10.1021/acs.bioconjchem.4c00335
292 Giacalone G, Quaillet M, Huang N, Nicolas V, Boulogne C, Gillet C, Fattal E, Bochot A, Hillaireau H.An injectable, nanostructured implant for the delivery of adenosine triphosphate: towards long-acting formulations of small, hydrophilic drugs. Drug Deliv Transl Res. 2024, 14(8):2146-2157 – https://doi.org/10.1007/s13346-024-01631-9
291 Lamaa D, Cailleau C, Vergnaud J, Mougin J, Bignon J, Alami M, Fattal E, Hamze A, Tsapis N Overcoming solubility challenges: Liposomal isoCoQ-Carbazole as a promising anti-Tumor agent for inoperable and radiation-insensitive cancers, 25, e202400062, 2024 – https://doi.org/10.1002/cbic.202400062
290 Landon G, Phan G, Fay F, Suhard D, Broggio D, Bô R, Bouvier-Capely C, Fattal E Bisphosphonate Liposomes for Cobalt and Strontium Decorporation, Health Physics 127(4), 463-475, 2024 – https://doi.org/10.1097/HP.0000000000001812
289 Tessier B, Moine L, Peramo A, Tsapis N, Fattal E. Poly(malic acid)-budesonide nanoconjugates embedded in microparticles for lung administration. Drug Delivery and Translational Research, 14, 2062–2078, 2024 – https://doi.org/10.1007/s13346-024-01571-4
288 Landon G, Phan G, Fay F, Bouvier-Capely C, Fattal E Nanotechnologies and controlled release formulations for the administration of bisphosphonates and their potential in radiation protection. Journal of Drug Delivery Sciences and Technology, 90, 105154, 2023 – https://doi.org/10.1016/j.jddst.2023.105154
287 Paoletti A*, Ly B, Cailleau C, Gao Fan, Péan de Ponfilly-Sotier M , Pascaud J, Rivière E, Yang L, Nwosu L, Elmesmari A, Reynaud F, Hita M, Paterson D, Reboud J, Fay F , Nocturne G, Tsapis N, McInnes I.B., Kurowska-Stolarska M, Fattal E*, Mariette X* Liposomal AntagomiR-155-5p restores anti-inflammatory macrophages and improves arthritis in pre-clinical models of Rheumatoid arthritis. Arthritis & Rhumatology, 2023 – https://doi.org/10.1002/art.42665.
286 Robin B, Mousnier L, Lê H, Grabowski N, Chapron D, Bellance-Mina O, Huang N, Agnely F, Fattal E, Tsapis N. PLA-PEG forming worm-like nanoparticles despite unfavorable packing parameter: formation mechanism, thermal stability and potential for cell internalization. International Journal of Pharmaceutics, 2023 Jul 21:123263 – https://doi.org/10.1016/j.ijpharm.2023.123263
285 Hussain S, Ur Rehman M, Arif A, Cailleau C, Gillet C, Saleem R, Noor H, Naqvi F, Jabeen A, Atta-Ur-Rahman, Iqbal Choudhary M, Fattal E, Tsapis N. Diclofenac prodrugs nanoparticles: an alternative and efficient treatment for rheumatoid arthritis? International Journal of Pharmaceutics, 2023 Jul 13:123227. https://doi.org/10.1016/j.ijpharm.2023.123227.
284 Ur Rehman M, Reynaud F, Lepetre S, Abreu S, Chaminade P, Fattal E* Tsapis N* Modulation of release and pharmacokinetics from nanoscale lipid prodrugs of dexamethasone with variable linkage chemistry. Journal of Controlled Release, 2023 – https://doi.org/10.1016/j.jconrel.2023.06.031
283 Tessier B, Tsapis N, Fattal E*, Moine L*, Emerging nanoparticle platforms to improve the administration of glucocorticoids. Journal of Controlled Release. 358, 273-292, 2023 – https://doi.org/10.1016/j.jconrel.2023.04.039
282 Japiassu KB, Fay F, Marengo A, Mendanha SA, Cailleau C, Louaguenouni Y, Wang Q, Denis S, Tsapis N, Nascimento TL, Lima EM, Fattal E. Hyaluronic acid-conjugated liposomes loaded with dexamethasone: a promising approach for the treatment of inflammatory diseases. International Journal of Pharmaceutics, 639, 122946, 2023 – https://doi.org/10.1016/j.ijpharm.2023.122946
281 Ortiz Peña N, Cherukula K, Even B, Ding-Kun J, Razafindrakoto S, Peng S, Silva A, Ménard Moyon C, Hillaireau H, Bianco A*, Fattal E *, Alloyeau D*, Gazeau F* Resolution of MoS2 nanosheets-induced pulmonary inflammation driven by nanoscale intracellular transformation and extracellular-vesicle shuttles. Advanced Materials, 35, 13, 2209615, 2023 – https://doi.org/10.1002/adma.202209615
280 Yu Z, Tsapis N, Fay F, Chen L, Karpus A, Shi X, Cailleau C, García Pérez S, Huang N, Vergnaud J, Mignani S, Majoral JP, Fattal E. Amphiphilic Phosphorus Dendrons Associated with Anti-inflammatory siRNA Reduce Symptoms in Murine Collagen-Induced Arthritis. Biomacromolecules, 24, 2, 667–677, 2023 – https://doi.org/10.1021/acs.biomac.2c01117
279 Japiassu KB, Fay F, Marengo A, Louaguenouni Y, Cailleau C, Denis S, Chapron D, Tsapis N, Nascimento TL, Lima EM, Fattal E. Interplay between mucus mobility and alveolar macrophage targeting of surface-modified liposomes. Journal of Controlled Release, 352, 15–24, 2022 – https://doi.org/10.1016/j.jconrel.2022.10.006
278 Twarog C, Fattal E, Noiray M, Illel B, Brayden D, Taverna M, Hillaireau H. Characterization of the physicochemical interactions between exenatide and two intestinal permeation enhancers: sodium caprate (C10) and salcaprozate sodium (SNAC). Int J Pharm. 626, 122131, 2022 – https://doi.org/10.1016/j.ijpharm.2022.122131
277 González-Sánchez E, Muñoz-Callejas A, Gómez-Román J, San Antonio E, Marengo A, Tsapis N, Bohne-Japiassu K, González-Tajuelo R, Pereda S, García-Pérez J, Cavagna L, González-Gay MÁ, Vicente-Rabaneda E, Meloni F, Fattal E, Castañeda S, Urzainqui A. Everolimus targeted nanotherapy reduces inflammation and fibrosis in scleroderma-related interstitial lung disease (SSc-ILD) developed by PSGL-1 deficient mice. Br J Pharmacol. 2022 Jun 21. https://doi.org/10.1111/bph.15898
276 Pinheiro do Nascimento L, Tsapis N, Reynaud F, Desmaële D, Moine L, Vergnaud J, Abreu S, Chaminade P, Fattal E. Mannosylation of budesonide palmitate nanoprodrugs for improved macrophage targeting. European Journal of Pharmaceutics and Biopharmaceutics, 2022 170:112-120. https://doi.org/10.1016/j.ejpb.2021.12.001
275 Simón-Vázquez R, Tsapis N, Lorscheider M, Rodríguez A, Calleja P, Mousnier L, de Miguel Villegas E, González-Fernández Á, Fattal E. Improving dexamethasone drug loading and efficacy in treating arthritis through a lipophilic prodrug entrapped into PLGA-PEG nanoparticles. Drug Delivery and Translational Research, 2022. https://doi.org/10.1007/s13346-021-01112-3
274 Mathieu C, Chamayou Q, Hyen Luong TT, Naud D, Mahuteau-Betzer F, Alami M, Fattal E, Messaoudi S, Vergnaud-Gauduchon J. Synthesis and antiproliferative activity of 6BrCaQ-TPP conjugates for targeting the mitochondrial heat shock protein TRAP1. European Journal of Medicinal Chemistry, 2022, 229, 114052 – https://doi.org/10.1016/j.ejmech.2021.114052
273 Toussaint B, Hillaireau H, Jaccoulet E, Cailleau C, Legrand P, Ambroise Y, Fattal E. Interspecies comparison of plasma metabolism and sample stabilization for quantitative bioanalyses: Application to (R)-CE3F4 in preclinical development, including metabolite identification by high-resolution mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2021, 1183, 122943 – https://doi.org/10.1016/j.jchromb.2021.122943
272 Toussaint B, Hillaireau H, Cailleau C, Ambroise Y, Fattal E.Stability, pharmacokinetics, and biodistribution in mice of the EPAC1 inhibitor (R)-CE3F4 entrapped in liposomes and lipid nanocapsules. Int J Pharm. 2021, 610:121213. https://doi.org 10.1016/j.ijpharm.2021.121213.
271 Racaniello GF, LaquintanaV, Vergnaud J, Lopedota A, Cutrignelli A, Lopalco A, Leonetti F, Franco M, Fiume M, Pontrelli, Gesualdo L, Fattal E, Denora N Development of purified glycogen derivatives as siRNA nanovectors. International Journal of Pharmaceutics, 608, 12112810, 2021 – https://doi.org/10.1016/j.ijpharm.2021.121128
270 Pandolfi L, Marengo A, Japiassu KB, Frangipane V, Tsapis N, Bincoletto V, Codullo V, Bozzini S, Morosini M, Lettieri S, Vertui V, Piloni D, Arpicco S, Fattal E, Meloni F. Liposomes Loaded with Everolimus and Coated with Hyaluronic Acid: A Promising Approach for Lung Fibrosis. International Journal of Molecular Science, 22(14) :7743, 2021 – https://doi.org/10.3390/ijms22147743
269 Twarog, C, McCartney, F, Harrison, SM, Illel, B, Fattal, E, Brayden DJ. Comparison of the effects of the intestinal permeation enhancers, SNAC and sodium caprate (C-10): Isolated rat intestinal mucosae and sacs. European journal of pharmaceutical sciences, 2021, 158, 105685 – https://doi.org/10.1016/j.ejps.2020.105685
268 Canioni R, Reynaud F, Leite-Nascimento T, Gueutin C, Guiblin N, Ghermani NE, Jayat C, Daull P, Garrigue JS, Fattal E, Tsapis N. Tiny dexamethasone palmitate nanoparticles for intravitreal injection: Optimization and in vivo evaluation. International Journal of Pharmaceutics https://doi.org/10.1016/j.ijpharm.2021.120509
267 Fattal, E, Fay, F, Nanomedicine-based delivery strategies for nucleic acid gene inhibitors in inflammatory diseases. Advanced drug delivery reviews, 2021, 175, 113809 – https://doi.org/10.1016/j.addr.2021.05.019
266 Gürcan, S, Tsapis, N, Reynaud, F, Denis, S, Vergnaud, J, Ozer, O, Fattal, E, Combining dexamethasone and TNF-α siRNA within the same nanoparticles to enhance anti-inflammatory effect. International Journal of Pharmaceutics, https://doi.org/10.1016/j.ijpharm.2021.120381
265 AH Mota, JM Andrade, MJ Rodrigues, L Custódio, MR Bronze, N Duarte, Baby, A, Rocha, J, Gaspar, MM, Simoes, S, Carvalheiro, M, Fattal, E, Almeida, AJ, Reis, CP, Synchronous insight of in vitro and in vivo biological activities of Sambucus nigra L. extracts for industrial uses. Industrial Crops and Products. https://doi.org/10.1016/j.indcrop.2020.112709
264 Bohr, A, Tsapis, N, Foged, C, Andreana, I, Yang, M, Fattal, E, Treatment of acute lung inflammation by pulmonary delivery of anti-TNF-alpha siRNA with PAMAM dendrimers in a murine model. European journal of pharmaceutics and biopharmaceutics, 2020, 156, 114-120. https://doi.org/10.1016/j.ejpb.2020.08.009
263 Deguettes, Q, Fattal, E, Moreau, M, Lego, E, Bochot, A, Controlled delivery of follicle-stimulating hormone in cattle. International journal of pharmaceutics, 590, 119904, 2020. https://doi.org/10.1016/j.ijpharm.2020.119904
262 Costamagna F, Hillaireau H, Vergnaud-Gauduchon J, Clarisse D, Jamgotchian L., Loreau O, Denis S, Gravel E, Doris E, Fattal E. Nanotoxicology at the particle/micelle frontier: influence of core-polymerization on the intracellular distribution, cytotoxicity, and genotoxicity of polydiacetylene micelles. Nanoscale, 12, 2452-2463, 2020. https://doi.org/10.1039/C9NR08714A
261 Yu Z, Reynaud F, Lorscheider M, Tsapis N, Fattal E. Nanomedicines for the delivery of glucocorticoids and nucleic acids as potential alternatives in the treatment of rheumatoid arthritis. Wires Nanomedicine and Nanobiotechnology, 12, 5, e1630, 2020. https://doi.org/10.1002/wnan.1630
260 Twarog C, Liu K, O’Brien PJ, Dawson KA, Fattal E, Illel B, Brayden DJ. A head-to-head Caco-2 assay comparison of the mechanisms of action of the intestinal permeation enhancers: SNAC and sodium caprate (C10). European journal of pharmaceutics and biopharmaceutics, 152, 95-107, 2020. https://doi.org/10.1016/j.ejpb.2020.04.023
259 Mathieu C, Messaoudi S, Fattal E, Vergnaud-Gauduchon J. Cancer drug resistance: rationale for drug delivery systems and targeted inhibition of HSP90 family proteins. Cancer Drug Resist 2019;2:381-98. http://dx.doi.org/10.20517/cdr.2019.26
258 Leng D, Kissi EO, Löbmann K, Thanki K, Fattal E, Rades T, Foged C, Yang M. Design of inhalable solid dosage forms of Budesonide and Theophylline for pulmonary combination therapy. AAPS PharmSciTech. 20, 3, 137, 2019. https://doi.org/10.1208/s12249-019-1344-9
257 Albert C, Beladjine M, Tsapis N, Fattal E, Agnely F, Huang N. Pickering emulsions: Preparation processes, key parameters governing their properties and potential for pharmaceutical applications. Journal of Controlled Release, 309, 302-332, 2019. https://doi.org/10.1016/j.jconrel.2019.07.003
256 Alshaer W, Zraikat M, Amer A, Nsairat H, Lafi Z, Alqudah D, Al Qadi E, Alsheleh T, Odeh F, Alkaraki A, Zihlif M, Bustanji Y, Fattal E, Awidi A, Encapsulation of echinomycin in cyclodextrin inclusion complexes into liposomes: in vitro anti-proliferative and anti-invasive activity in glioblastoma, RSC Advances, 9, 30976-30988, 2019. https://doi.org/10.1039/C9RA05636J
255 Pinto Carneiro S, Moine L, Tessier B, Nicolas V, Henrique dos Santos OD, Fattal E, Pyrazinoic acid-Poly(malic acid) biodegradable nanoconjugate for efficient intracellular delivery. Precision Nanomedicine 2(3), 303-317, 2019. https://doi.org/10.33218/prnano2(3).190523.1
254 Pandolfi L, Frangipane V, Bocca C, Marengo A, Tarro Genta E, Bozzini S, Morosini M, D’Amato M, Vitulo S, Monti M, Comolli G, Scupoli MT, Fattal E, Arpicco S, Meloni F. Hyaluronic Acid-Decorated Liposomes as Innovative Targeted Delivery System for Lung Fibrotic Cells. Molecules. (18). pii: E3291, 2019. https://doi.org/10.3390/molecules24183291
253 Lorscheider M, Tsapis N, Simon-Vasquez R, Guiblin N, Ghermani N, Reynaud F, Canioni R, Abreu S, Chaminade P, Fattal E. Nanoscale lipophilic prodrugs of dexamethasone with enhanced pharmacokinetics. Molecular Pharmaceutics, 16, 7, 2999–3010, 2019. https://doi.org/10.1021/acs.molpharmaceut.9b00237
252 Gazzano E, Buondonno I, Marengo A, Rolando B, Chegaev K, Kopecka J, Saponara S, Sorge M, Hattinger CM, Gasco A, Fruttero R, Brancaccio M, Serra M, Stella B, Fattal E, Arpicco S, Riganti C. Hyaluronated liposomes containing H2S-releasing doxorubicin are effective against P-glycoprotein-positive/doxorubicin-resistant osteosarcoma cells and xenografts. Cancer Letters, 456, 29-39, 2019. https://doi.org/10.1016/j.canlet.2019.04.029
251 Lorscheider M., Tsapis N., Ur-Rehman M., Gaudin F., Stolfa I., Abreu S., Mura S., Chaminade P., Espeli M., Fattal E., Dexamethasone palmitate nanoparticles: An efficient treatment for rheumatoid arthritis. Journal of Controlled Release, 296 179-189, 2019. https://doi.org/10.1016/j.jconrel.2019.01.015
250 Pallotta A., Clarot I., Sobocinski J., Fattal E., Boudier A., Nanotechnologies for Medical Devices: Potentialities and Risks. ACS Applied Bio Materials, 2 (1), 1 –13, 2019. https://doi.org/10.1021/acsabm.8b00612
249 Chvatal A, Ambrus R, Party P, Katona G, Jójárt-Laczkovich O, Szabó-Révész P, Fattal E, Tsapis N. Formulation and Comparison Of Spray Dried Non-Porous And Large Porous Particles Containing Meloxicam For Pulmonary Drug Delivery. International Journal of Pharmaceutics,559, 68-75, 2019. https://doi.org/10.1016/j.ijpharm.2019.01.034
248 Barillet S., Fattal E., Mura S., Tsapis N., Pallardy M., Hillaireau H., Kerdine-Römer S., Immunotoxicity of poly (lactic-co-glycolic acid) nanoparticles: influence of surface properties on dendritic cell activation. Nanotoxicology, 13:5, 606-622, 2019. https://doi.org/10.1080/17435390.2018.1564078
247 Mura S, Fattal E, Nicolas J. From Poly (Alkyl Cyanoacrylate) to Squalene as Core Material to Design Nanomedicines. Journal of Drug Targeting, 27:5-6, 470-501, 2019. https://doi.org/10.1080/1061186x.2019.1579822
246 Deschamps F, Isoardo T, Denis S, Tsapis N, Tselikas L, Nicolas V, Paci A, Fattal E, de Baere T, Huang N, Moine L. Biodegradable Pickering emulsions of Lipiodol for liver trans-arterial chemoembolization. Acta Biomaterialia, 87, 177-186, 2019. https://doi.org/10.1016/j.actbio.2019.01.054
245 Marengo A., Forciniti S., Dando I., Elisa DallaPozza E., Stella B., Tsapis N. Yagoubi N., Fanelli G., Fattal E., Heeschen C., Palmieri M., Arpicco S. Pancreatic cancer stem cell proliferation is strongly inhibited by diethyldithiocarbamate copper complex loaded into hyaluronic acid decorated liposomes. Biochimica et Biophysica Acta (BBA) – General Subjects 1863(1); 61-72, 2019. https://doi.org/10.1016/j.bbagen.2018.09.018
244 Twarog C, Fattah S, Heade J., Maher S., Fattal E., Brayden DJ. Intestinal Permeation Enhancers for Oral Delivery of Macromolecules: A Comparison between Salcaprozate Sodium (SNAC) and Sodium Caprate (C10). Pharmaceutics, 11(2), 78, 2019. https://doi.org/10.3390/pharmaceutics11020078
243 N’Guessan A., Fattal E., Chapron D., Gueutin C., Koffi A., Tsapis N., Dexamethasone palmitate large porous particles: a controlled release formulation for lung delivery of corticosteroids. European Journal of Pharmaceutical Sciences, 113, 185-192, 2018. https://doi.org/10.1016/j.ejps.2017.09.013
242 Leng D., Thanki K., Fattal E., Foged C., Yang M. Engineering of budesonide-loaded lipid-polymer hybrid nanoparticles using a quality-by-design approach. International Journal of Pharmaceutics 548, (2), 740-746, 2018. https://doi.org/10.1016/j.ijpharm.2017.08.094
241 Tortolano L., Saunier J., Hammami S., Manerlax K., Matmati H., Do B., Jubeli E., Fattal E., Yagoubi N. Restructuration kinetics of amphiphilic intraocular lenses during aging. Colloids and Surface B, 161, (1), 20-432, 2018. https://doi.org/10.1016/j.colsurfb.2017.11.007
240 Alshaer, W., Hillaireau, H., Vergnaud, J., Mura S., Deloménie C., Sauvage F., Ismail S., Fattal, E., Aptamer-guided siRNA-loaded nanomedicines for systemic gene silencing in CD-44 expressing murine triple-negative breast cancer model. Journal of Controlled Release – 271, 198-106, 2018. https://doi.org/10.1016/j.jconrel.2017.12.022
239 Deriu M.A., Tsapis N., Noiray M., Grasso G., El Brahmi N., Mignani S, Majoral J.P., Fattal E. Danani A. Elucidating the Role of Surface Chemistry on Cationic Phosphorus Dendrimer-siRNA Complexation. Nanoscale – 10, 10952-10962, 2018. https://doi.org/10.1039/C8NR01928B
238 Sauvage F, Fattal E, Al-Shaer W, Denis S, Brotin E, Denoyelle C, Blanc-Fournier C, Toussaint B, Messaoudi S, Alami M, Barratt G, Vergnaud-Gauduchon J. Antitumor activity of nanoliposomes encapsulating the novobiocin analogue 6BrCaQ in a triple-negative breast cancer model in mice. Cancer Letters -432, 103-111, 2018. https://doi.org/10.1016/j.canlet.2018.06.001
237 Giacalone G., Tsapis N., Mousnier L., Chacun H., Fattal E. PLA-PEG nanoparticles improve the anti-inflammatory effect of Rosiglitazone on macrophages by enhancing drug uptake compared to free Rosiglitazone. Materials, 11(10), 1845, 2018. https://doi.org/10.1016/j.canlet.2018.06.001
236 Alshaer W., Hillaireau H., Fattal E., Aptamer-guided nanomedicines for anticancer drug delivery. Advanced drug delivery reviews, 134, 122-137;2018. https://doi.org/10.1016/j.addr.2018.09.011
235 Albert C, Huang N, Tsapis N, Geiger S, Rosilio V, Mekhloufi G, Chapron D, Robin B, Beladjine M, Nicolas V, Fattal E, Agnely F. Bare and Sterically Stabilized PLGA Nanoparticles for the Stabilization of Pickering Emulsions. Langmuir. 2018 34(46):13935-13945. https://pubs.acs.org/doi/abs/10.1021/acs.langmuir.8b02558
234 Grivès S, Phan G, Bouvier-Capely C, Suhard D, Rebière F, Agarande M, Fattal E. Compared in vivo efficiency of nanoemulsions unloaded and loaded with calixarene and soapy water in the treatment of superficial wounds contaminated by uranium. Chemico-Biological Interactions, 267:33–39, 2017. https://doi.org/10.1016/j.cbi.2016.11.030
233 Martens TF, Peynshaert K, Nascimento TL, Fattal E, Karlstetter M, Langmann T, Picaud S, Demeester J, De Smedt SC, Remaut K, Braeckmans K. Effect of hyaluronic acid-binding to lipoplexes on intravitreal drug delivery for retinal gene therapy. European Journal of Pharmaceutical Sciences 103:27-35, 2017. https://doi.org/10.1016/j.ejps.2017.02.027
232 Sauvage F, Messaoudi S, Fattal E, Barratt G, Vergnaud-Gauduchon J. Heat shock proteins and cancer: How can nanomedicine be harnessed? Journal of Controlled Release, 248:133-143, 2017. https://doi.org/10.1016/j.jconrel.2017.01.013
231 Manconi M., Manca M. L., Valenti D., Escribano E., Hillaireau H., Fadda A. M., Fattal E., Chitosan and hyaluronan coated liposomes for pulmonary administration of curcumin. International Journal of Pharmaceutics 1(15), 203-210, 2017. https://doi.org/10.1016/j.ijpharm.2017.04.044
230 Gokce EH, Tuncay Tanrıverdi S, Eroglu I, Tsapis N, Gokce G, Tekmen I, Fattal E, Ozer O. Wound healing effects of collagen-laminin dermal matrix impregnated with resveratrol loaded hyaluronic acid-DPPC microparticles in diabetic rats. European journal of pharmaceutics and biopharmaceutics, 119, 17-27, 2017. https://doi.org/10.1016/j.ejpb.2017.04.027
229 Cosco D, Tsapis N, Nascimento TL, Fresta M, Chapron D, Taverna M, Arpicco S, Fattal E. Polysaccharide-coated liposomes by post-insertion of a hyaluronan-lipid conjugate. Colloids and Surfaces B: Biointerfaces 158C, 119-126, 2017. https://doi.org/10.1016/j.colsurfb.2017.06.029
228 Bohr A, Tsapis N, Andreana I, Chamarat A, Foged C, Delomenie C, Noiray M, El Brahmi N, Majoral JP, Mignani S, Fattal E. Anti-inflammatory effect of anti-TNF-α siRNA cationic phosphorous dendrimers nanocomplexes administered intranasally in a murine acute lung injury model. Biomacromolecules, 18 (8), 2379–2388, 2017. https://doi.org/10.1021/acs.biomac.7b00572
227 Deschamps F, Moine L, Isoardo T, Tselikas L, Paci A, Mir LM, Huang N, Fattal E, de Baère T. Parameters for stable water-in-oil lipiodol emulsion for liver trans-arterial chemoembolization. CardioVascular and Interventional Radiology, 40, (12), 1927–1932, 2017. https://doi.org/10.1007/s00270-017-1763-5
226 Boissenot T., Bordat A., Larrat B., Varna M., Chacun H., Paci A., Poinsignon V., Fattal E., Tsapis N., Ultrasound-induced mild hyperthermia improves the anticancer efficacy of both Taxol® and paclitaxel-loaded nanocapsules. Journal of Controlled Release, 264, 219-227, 2017. https://doi.org/10.1016/j.jconrel.2017.08.041
225 Teixeira HF, Bruxel F, Fraga M, Schuh RS, Zorzi GK, Matte U, Fattal E. Cationic nanoemulsions as nucleic acids delivery systems. International Journal of Pharmaceutics 534, (1–2), 356-367, 2017. https://doi.org/10.1016/j.ijpharm.2017.10.030
224 Ruge C., Hillaireau H., Grabowski N., Beck-Broichsitter M., Canadas O., Tsapis N., Casals C., Nicolas J., Fattal, E. Pulmonary surfactant protein a – mediated enrichment of surface-decorated polymeric nanoparticles in alveolar macrophages. Molecular Pharmaceutics. 13(12):4168-4178, 2016. https://doi.org/10.1021/acs.molpharmaceut.6b00773
223 Boissenot T, Fattal E, Bordat A, Houvenagel S, Valette J, Chacun H, Gueutin C, Tsapis N. Paclitaxel-Loaded PEGylated Nanocapsules of Perfluorooctyl Bromide as Theranostic Agents. European Journal of Pharmaceutics and Biopharmaceutics, 108:136-144, 2016. https://doi.org/10.1016/j.ejpb.2016.08.017
222 Leite Nascimento T., Hillaireau H., Vergnaud J., Rivano M., Deloménie C., Courilleau D., Arpicco S., Soo Suk J., Hanes J., Fattal E. Hyaluronic acid-conjugated lipoplexes for targeted delivery of siRNA in a murine metastatic lung cancer model. International Journal of Pharmaceutics. 514(1):103-111, 2016. https://doi.org/10.1016/j.ijpharm.2016.06.125
221 Boissenot T., Bordat A., Fattal E., Tsapis N. Ultrasound-triggered drug delivery for cancer treatment using drug delivery systems: From theoretical considerations to practical applications. Journal of Controlled Release, 241, 10, 144–163, 2016. https://doi.org/10.1016/j.jconrel.2016.09.026
220 Diou O, Brûlet A, Pehau-Arnaudet G, Morvan E, Berti R, Astafyeva K, Taulier N, Fattal E, Tsapis N. PEGylated nanocapsules of perfluorooctyl bromide: Mechanism of formation, influence of polymer concentration on morphology and mechanical properties. Colloids and Surfaces B: biointerfaces, 146:762-769, 2016. https://doi.org/10.1016/j.colsurfb.2016.07.033
219 Leite Nascimento T., Hillaireau H., Vergnaud J., Fattal E. Lipid based nanosystems for CD44 targeting in cancer treatment: recent significant advances, ongoing challenges, and unmet needs. Nanomedicine, 12(1):135-46, 2016. https://doi.org/10.2217/nnm-2016-5000
218 Dosio F., Arpicco S., Stella B., Fattal E. Hyaluronic acid for anticancer drug and nucleic acid delivery Advanced Drug Delivery Reviews, 97, 204-236,2016. https://doi.org/10.1016/j.addr.2015.11.011
217 Ruge C., Bohr A., Beck-Broichsitter M., Nicolas V., Tsapis N., Fattal E. Disintegration of nano-embedded microparticles after deposition on mucus: a mechanistic study. Colloids and Surfaces B: biointerfaces, 139,219–227, 2016. https://doi.org/10.1016/j.colsurfb.2015.12.017
216 Grabowski, N., Hillaireau, H., Vergnaud, J., Nicolas V., Tsapis, N., Kerdine-Romer S., Fattal, E., Surface-modified biodegradable nanoparticles’ impact on cytotoxicity and inflammation response on a co-culture of lung epithelial cells and human-like macrophages. Journal of Biomedical Nanotechnology, 12, 135-146, 2016. https://doi.org/10.1166/jbn.2016.2126
215 Nascimento T L, Hillaireau H, Fattal E. Noiray M., Bourgaux C., Arpicco S., Pehau-Arnaudet G., Taverna M., Cosco D., Tsapis N., Fattal E. Supramolecular organization, and siRNA binding of hyaluronic acid-coated lipoplexes for targeted delivery to CD44 receptor. Langmuir, 31(41):11186-11194, 2015. https://doi.org/10.1021/acs.langmuir.5b01979
214 Pham D., Fattal E., Tsapis N., Pyrazinamide-loaded poly(lactide-co-glycolide) nanoparticles: Optimization by experimental design. Journal of Drug Delivery Science and Technology, 30, 384-390, 2015. https://doi.org/10.1016/j.jddst.2015.07.006
213 Santiago, L, Hillaireau, H., Grabowski, N., Mura, S., Nascimento, T., Dufort, S., Coll, J-L, Tsapis, N., Fattal, E., Compared in vivo toxicity in mice of lung delivered biodegradable and non-biodegradable nanoparticles. Nanotoxicology, 17:1-11, 2015. https://doi.org/10.3109/17435390.2015.1054908
212 Reynaud F., Tsapis N., Guterres S.S., Pohlmann A.R., Fattal E., Pectin beads loaded with chitosan-iron microspheres for specific colonic adsorption of ciprofloxacin. Journal of Drug Delivery Science and Technology, 30, 494-500, 2015.
211 Fattal E, Tsapis N, Phan G., Novel drug delivery systems for actinides (uranium and plutonium) decontamination agents. Advanced Drug Delivery Reviews, 90, 40-54 2015.
210 Pham DD, Grégoire N, Couet W, Gueutin C, Fattal E, Tsapis N., Pulmonary delivery of pyrazinamide-loaded large porous particles. European Journal of Pharmaceutics and Biopharmaceutics, 94, 241-250, 2015.
209 Giacalone, G., Hillaireau, H., Fattal, E., Improving bioavailability and biodistribution of anti-HIV chemotherapy European Journal of Pharmaceutical Sciences. 75: 40-53, 2015.
208 Novell, A., Al Sabbagh, C., Escoffre, J.M., Gaillard, C., Tsapis, N., Fattal, E., Bouakaz, A., Focused ultrasound influence on calcein-loaded thermosensitive stealth liposomes. Int J Hyperthermia. 31:349-358, 2015.
207 Grivès, S., Phan, G., Morat, G., Suhard, D., Rebière, F., Fattal, E., Ex vivo uranium decontamination efficiency on wounded skin and in vitro skin toxicity of a calixarene-loaded nanoemulsion. Journal of Pharmaceutical Sciences. 104(6):2008-2017, 2015.
206 Eroğlu İ, Gökçe EH, Tsapis N, Tanrıverdi ST, Gökçe G, Fattal E, Özer Ö Evaluation of characteristics and in vitro antioxidant properties of RSV loaded hyaluronic acid-DPPC microparticles as a wound healing system. Colloids and Surface B Biointerfaces,126:50-7, 2015
205 Pham D, Fattal E, Tsapis N. Pulmonary drug delivery systems for tuberculosis treatment. International Journal of Pharmaceutics. 478(2):517-29, 2015.
204 Cosco D, Paolino D, Angelis FD, Cilurzo F, Celia C, Marzio LD, Russo D, Tsapis N, Fattal E, Fresta M. Aqueous-core PEG-coated PLA nanocapsules for an efficient entrapment of water-soluble anticancer drugs and a smart therapeutic response. European Journal of Pharmaceutics and Biopharmaceutics 89:30-9, 2015.
203 Grabowski N, Hillaireau H, Vergnaud J, Tsapis N1, Pallardy M, Kerdine-Römer S, Fattal E. Surface coating mediates the toxicity of polymeric nanoparticles towards human-like macrophages. International Journal of Pharmaceutics. 482(1-2):75-83, 2015.
202 Cosco, D., Fattal, E., Fresta, M., Tsapis N., Perfluorocarbon-loaded micro and nanosystems for medical imaging: a state of the art. Journal of Fluorine Chemistry. 171:18-26, 2015.
201 Al Sabbagh, C, Tsapis, N, Novell, A., Calleja-Gonzalez, P., Escoffre, JM, Bouakaz A, Chacun, H., Denis, S, Vergnaud, J, Gueutin, C, Fattal, E, Formulation and Pharmacokinetics of thermosensitive stealth® liposomes encapsulating 5-Fluorouracil. Pharmaceutical Research, 32(5):1585-603, 2015.
200 Alshaer, W., Hillaireau, H., Vergnaud, J.,Ismail S., Fattal, E., Functionalizing liposomes with anti-CD44 aptamer for selective targeting of cancer cells. Bioconjugate Chemistry, 26 (7), 1307–1313, 2015.
199 Fattal, E., Grabowski, N., Mura, S., Vergnaud, J., Tsapis, N., Hillaireau, H., Lung Toxicity of Biodegradable Nanoparticles. Journal of Biomedical Nanotechnology, 10(10), 2852-2864, 2014.
198 Fattal, E., Tsapis, N., Nanomedicine technology: current achievements and new trends. Clinical and Translational Imaging, 2(1), 77-87, 2014.
197 Belhomme-Henry, C., Phan, G., Huang, N., Bouvier, C., Rebiere, F., Agarande, M., Fattal, E., Texturing formulations for uranium skin decontamination. Pharmaceutical Development and Technology, 19(6), 692-701, 2014.
196 Diou, O., Fattal, E., Delplace, V., Mackiewicz, N., Nicolas, J., Meriaux, S., Valette, J., Robic, C., Tsapis, N., RGD decoration of PEGylated polyester nanocapsules of perfluorooctyl bromide for tumor imaging: influence of pre- or post-functionalization on capsule morphology. European Journal of Pharmaceutics and Biopharmaceutics, 87(1), 170-177, 2014.
195 Bol, L., Galas, J.C., Hillaireau, H., Le Potier, I., Nicolas, V., Haghiri-Gosnet, A.M., Fattal, E., Taverna, M., A microdevice for parallelized pulmonary permeability studies. Biomedical Microdevices, 16(2), 277-285, 2014.
194 Jafari, S., Diou, O., Mamou, J., Renault, G., Fattal, E., Tsapis, N., Bridal, S.L., High-frequency (20 to 40 MHz) acoustic response of liquid-filled nanocapsules. IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 61(1), 5-15, 2014.
193 Bruxel, F., Bochot, A., Diel, D., Wild, L., Carvalho, E.L., Cojean, S., Loiseau, P.M., Fattal, E., Teixeira, H.F., Adsorption of antisense oligonucleotides targeting malarial topoisomerase II on cationic nanoemulsions optimized by a full factorial design. Current Topics in Medicinal Chemistry, 14(9), 1161-1171, 2014.
192 Mousnier, L., Huang, N., Morvan, E., Fattal, E., Tsapis, N., Influence of polymer end-chemistry on the morphology of perfluorohexane polymeric microcapsules intended as ultrasound contrast agents. International Journal of Pharmaceutics, 471(1-2), 10-17, 2014.
191 Giacalone, G., Hillaireau, H., Capiau, P., Chacun, H., Reynaud, F., Fattal, E., Stabilization, and cellular delivery of chitosan-polyphosphate nanoparticles by incorporation of iron. Journal of Controlled Release, 194, 211-219, 2014.
190 Ismail, S., Alshaer, W., Ababneh, N., Fattal, E., Aptamers: Promising Molecules for Cancer Stem Cell Targeting. Journal of Molecular and Genetic Medicine, 7(90), 1-10, 2013.
189 Hamoudi, M.C., Saunier, J., Gueutin, C., Fattal, E., Bochot, A., Beads made of alpha-cyclodextrin and soybean oil: the drying method influences bead properties and drug release. Drug Development and Industrial Pharmacy, 39(9), 1306-1314, 2013.
188 Gomez-Gaete, C., Bustos, G.L., Godoy, R.R., Saez, C.K., Novoa, G.P., Fernandez, E.M., Tsapis, N., Fattal, E., Successful factorial design for the optimization of methylprednisolone encapsulation in biodegradable nanoparticles. Drug Development and Industrial Pharmacy, 39(2), 310-320, 2013.
187 Pham, D.D., Fattal, E., Ghermani, N., Guiblin, N., Tsapis, N., Formulation of pyrazinamide-loaded large porous particles for the pulmonary route: avoiding crystal growth using excipients. International Journal of Pharmaceutics, 454(2), 668-677, 2013.
186 Tobar-Grande, B., Godoy, R., Bustos, P., von Plessing, C., Fattal, E., Tsapis, N., Olave, C., Gomez-Gaete, C., Development of biodegradable methylprednisolone microparticles for treatment of articular pathology using a spray-drying technique. International Journal of Nanomedicine, 82065-2076, 2013.
185 Grabowski, N., Hillaireau, H., Vergnaud, J., Santiago, L.A., Kerdine-Romer, S., Pallardy, M., Tsapis, N., Fattal, E., Toxicity of surface-modified PLGA nanoparticles toward lung alveolar epithelial cells. International Journal of Pharmaceutics, 454(2), 686-694, 2013.
184 Arpicco, S., Lerda, C., Dalla Pozza, E., Costanzo, C., Tsapis, N., Stella, B., Donadelli, M., Dando, I., Fattal, E., Cattel, L., Palmieri, M., Hyaluronic acid-coated liposomes for active targeting of gemcitabine. European Journal of Pharmaceutics and Biopharmaceutics, 85(3), 373-380, 2013.
183 Phan, G., Semili, N., Bouvier-Capely, C., Landon, G., Mekhloufi, G., Huang, N., Rebiere, F., Agarande, M., Fattal, E., Calixarene cleansing formulation for uranium skin contamination. Health Physics, 105(4), 382-389, 2013.
182 Ababneh, N., Alshaer, W., Allozi, O., Mahafzah, A., El-Khateeb, M., Hillaireau, H., Noiray, M., Fattal, E., Ismail, S., In vitro selection of modified RNA aptamers against CD44 cancer stem cell marker. Nucleic Acid Therapeutics, 23(6), 401-407, 2013.
181 Giacalone, G., Bochot, A., Fattal, E., Hillaireau, H., Drug-Induced Nanocarrier Assembly as a Strategy for the Cellular Delivery of Nucleotides and Nucleotide Analogues. Biomacromolecules, 14(3), 737-742, 2013.
180 Dalla Pozza, E., Lerda, C., Costanzo, C., Donadelli, M., Dando, I., Zoratti, E., Scupoli, M.T., Beghelli, S., Scarpa, A., Fattal, E., Arpicco, S., Palmieri, M., Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity. Biochimica et Biophysica Acta, 1828(5), 1396-1404, 2013.
179 Arpicco, S., De Rosa, G., Fattal, E., Lipid-Based Nanovectors for Targeting of CD44-Overexpressing Tumor Cells. Journal of drug delivery, 2013860780-860780, 2013.
178 Diou, O., Tsapis, N., Giraudeau, C., Valette, J., Gueutin, C., Bourasset, F., Zanna, S., Vauthier, C., Fattal, E., Long circulating perfluorooctyl bromide nanocapsules for tumor imaging by 19FMRI. Biomaterials, 33(22), 5593-5602, 2012.
177 Xiong, B., Pallandre, A., le Potier, I., Audebert, P., Fattal, E., Tsapis, N., Barratt, G., Taverna, M., Electrophoretic mobility measurement by laser Doppler velocimetry and capillary electrophoresis of micrometric fluorescent polystyrene beads. Analytical Methods, 4(1), 183-189, 2012.
176 Reul, R., Tsapis, N., Hillaireau, H., Sancey, L., Mura, S., Recher, M., Nicolas, J., Coll, J.-L., Fattal, E., Near infrared labeling of PLGA for in vivo imaging of nanoparticles. Polymer Chemistry, 3(3), 694-702, 2012.
175 Nascimento, T.L., Hillaireau, H., Fattal, E., Nanoscale particles for lung delivery of siRNA. Journal of Drug Delivery Science and Technology, 22(1), 99-108, 2012.
174 Menard, N., Tsapis, N., Poirier, C., Arnauld, T., Moine, L., Lefoulon, F., Pean, J.-M., Fattal, E., Drug solubilization and in vitro toxicity evaluation of lipoamino acid surfactants. International Journal of Pharmaceutics, 423(2), 312-320, 2012.
173 Menard, N., Tsapis, N., Poirier, C., Arnauld, T., Moine, L., Gignoux, C., Lefoulon, F., Pean, J.-M., Fattal, E., Novel Surfactants with Diglutamic Acid Polar Head Group: Drug Solubilization and Toxicity Studies. Pharmaceutical Research, 29(7), 1882-1896, 2012.
172 Hamoudi, M.C., Bourasset, F., Domergue-Dupont, V., Gueutin, C., Nicolas, V., Fattal, E., Bochot, A., Formulations based on alpha cyclodextrin and soybean oil: an approach to modulate the oral release of lipophilic drugs. Journal of Controlled Release, 161(3), 861-867, 2012.
171 Dufay Wojcicki, A., Hillaireau, H., Nascimento, T.L., Arpicco, S., Taverna, M., Ribes, S., Bourge, M., Nicolas, V., Bochot, A., Vauthier, C., Tsapis, N., Fattal, E., Hyaluronic acid-bearing lipoplexes: physico-chemical characterization and in vitro targeting of the CD44 receptor. Journal of Controlled Release, 162(3), 545-552, 2012.
170 Diou, O., Tsapis, N., Fattal, E., Targeted nanotheranostics for personalized cancer therapy. Expert Opinion on Drug Delivery, 9(12), 1475-1487, 2012.
169 Bochot, A., Fattal, E., Liposomes for intravitreal drug delivery: A state of the art. Journal of Controlled Release, 161(2), 628-634, 2012.
168 Reynaud, F., Tsapis, N., Deyme, M., Vasconcelos, T.G., Gueutin, C., Guterres, S.S., Pohlmann, A.R., Fattal, E., Spray-dried chitosan-metal microparticles for ciprofloxacin adsorption: Kinetic and equilibrium studies. Soft Matter, 7(16), 7304-7312, 2011.
167 Trichard, L., Chaminade, P., Grossiord, J.L., Le Bas, G., Huang, N., Durand, D., Fattal, E., Bochot, A., Beads made of alpha-cyclodextrin and vegetable oils: oil composition and physicochemical properties influence bead feasibility and properties. Journal of Drug Delivery Science and Technology, 21(2), 189-194, 2011.
166 Bruxel, F., Cojean, S., Bochot, A., Teixeira, H., Bories, C., Loiseau, P.M., Fattal, E., Cationic nanoemulsion as a delivery system for oligonucleotides targeting malarial topoisomerase II. International Journal of Pharmaceutics, 416(2), 402-409, 2011.
165 Hamoudi, M., Fattal, E., Gueutin, C., Nicolas, V., Bochot, A., Beads made of cyclodextrin and oil for the oral delivery of lipophilic drugs: in vitro studies in simulated gastro-intestinal fluids. International Journal of Pharmaceutics, 416(2), 507-514, 2011.
164 Cruz, L., Fattal, E., Tasso, L., Freitas, G.C., Carregaro, A.B., Guterres, S.S., Pohlmann, A.R., Tsapis, N., Formulation, and in vivo evaluation of sodium alendronate spray-dried microparticles intended for lung delivery. Journal of Controlled Release, 152(3), 370-375, 2011.
163 Spagnul, A., Bouvier-Capely, C., Phan, G., Landon, G., Tessier, C., Suhard, D., Rebiere, F., Agarande, M., Fattal, E., Ex vivo decrease in uranium diffusion through intact and excoriated pig ear skin by a calixarene nanoemulsion. European Journal of Pharmaceutics and Biopharmaceutics, 79(2), 258-267, 2011.
162 Sandolo, C., Pechine, S., Le Monnier, A., Hoys, S., Janoir, C., Coviello, T., Alhaique, F., Collignon, A., Fattal, E., Tsapis, N., Encapsulation of Cwp84 into pectin beads for oral vaccination against Clostridium difficile. European Journal of Pharmaceutics and Biopharmaceutics, 79(3), 566-573, 2011.
161 Menard, N., Tsapis, N., Poirier, C., Arnauld, T., Moine, L., Lefoulon, F., Pean, J.M., Fattal, E., Physicochemical characterization and toxicity evaluation of steroid-based surfactants designed for solubilization of poorly soluble drugs. European Journal of Pharmaceutical Sciences, 44(5), 595-601, 2011.
160 Mura, S., Hillaireau, H., Nicolas, J., Le Droumaguet, B., Gueutin, C., Zanna, S., Tsapis, N., Fattal, E., Influence of surface charge on the potential toxicity of PLGA nanoparticles towards Calu-3 cells. International Journal of Nanomedicine, 62591-2605, 2011.
159 Mura, S., Hillaireau, H., Nicolas, J., Kerdine-Roemer, S., Le Droumaguet, B., Delomenie, C., Nicolas, V., Pallardy, M., Tsapis, N., Fattal, E., Biodegradable Nanoparticles Meet the Bronchial Airway Barrier: How Surface Properties Affect Their Interaction with Mucus and Epithelial Cells. Biomacromolecules, 12(11), 4136-4143, 2011.
158 Khoder, M., Tsapis, N., Fattal, E., Mechanisms of antibiotic resistance and delivery strategies to prevent its emergence. Journal of Drug Delivery Science and Technology, 20(6), 407-418, 2010.
157 Urbinati, G., Marsaud, V., Plassat, V., Fattal, E., Lesieur, S., Renoir, J.M., Liposomes loaded with histone deacetylase inhibitors for breast cancer therapy. International Journal of Pharmaceutics, 397(1-2), 184-193, 2010.
156 Urbinati, G., Audisio, D., Marsaud, V., Plassat, V., Arpicco, S., Sola, B., Fattal, E., Renoir, J.M., Therapeutic Potential of New 4-hydroxy-tamoxifen-Loaded pH-gradient Liposomes in a Multiple Myeloma Experimental Model. Pharmaceutical Research, 27(2), 327-339, 2010.
155 Spagnul, A., Bouvier-Capely, C., Phan, G., Rebiere, F., Fattal, E., Calixarene-Entrapped Nanoemulsion for Uranium Extraction from Contaminated Solutions. Journal of Pharmaceutical Sciences, 99(3), 1375-1383, 2010.
154 Spagnul, A., Bouvier-Capely, C., Phan, G., Rebiere, F., Fattal, E., A new formulation containing calixarene molecules as an emergency treatment of uranium skin contamination. Health Physics, 99(3), 430-434, 2010.
153 Spagnul, A., Bouvier-Capely, C., Adam, M., Phan, G., Rebiere, F., Fattal, E., Quick and efficient extraction of uranium from a contaminated solution by a calixarene nanoemulsion. International Journal of Pharmaceutics, 398(1-2), 179-184, 2010.
152 Khoder, M., Tsapis, N., Domergue-Dupont, V., Gueutin, C., Fattal, E., Removal of residual colonic ciprofloxacin in the rat by activated charcoal entrapped within zinc-pectinate beads. European Journal of Pharmaceutical Sciences, 41(2), 281-288, 2010.
151 Giraudeau, C., Flament, J., Marty, B., Boumezbeur, F., Meriaux, S., Robic, C., Port, M., Tsapis, N., Fattal, E., Giacomini, E., Lethimonnier, F., Le Bihan, D., Valette, J., A New Paradigm for High-Sensitivity F-19 Magnetic Resonance Imaging of Perfluorooctylbromide. Magnetic Resonance in Medicine, 63(4), 1119-1124, 2010.
150 Fritsch, P., Serandour, A.L., Gremy, O., Phan, G., Tsapis, N., Fattal, E., Benech, H., Deverre, J.R., Poncy, J.L., Structure of a single model to describe plutonium and americium decorporation by dtpa treatments. Health Physics, 99(4), 553-559, 2010.
149 Diaz-Lopez, R., Tsapis, N., Santin, M., Bridal, S.L., Nicolas, V., Jaillard, D., Libong, D., Chaminade, P., Marsaud, V., Vauthier, C., Fattal, E., The performance of PEGylated nanocapsules of perfluorooctyl bromide as an ultrasound contrast agent. Biomaterials, 31(7), 1723-1731, 2010.
148 Diaz-Lopez, R., Tsapis, N., Fattal, E., Liquid Perfluorocarbons as Contrast Agents for Ultrasonography and F-19-MRI. Pharmaceutical Research, 27(1), 1-16, 2010.
147 Chenal, M., Mura, S., Marchal, C., Gigmes, D., Charleux, B., Fattal, E., Couvreur, P., Nicolas, J., Facile Synthesis of Innocuous Comb-Shaped Polymethacrylates with PEG Side Chains by Nitroxide-Mediated Radical Polymerization in Hydroalcoholic Solutions. Macromolecules, 43(22), 9291-9303, 2010.
146 Taetz, S., Bochot, A., Surace, C., Arpicco, S., Renoir, J.M., Schaefer, U.F., Marsaud, V., Kerdine-Roemer, S., Lehr, C.M., Fattal, E., Hyaluronic Acid-Modified DOTAP/DOPE Liposomes for the Targeted Delivery of Anti-Telomerase siRNA to CD44-Expressing Lung Cancer Cells. Oligonucleotides, 19(2), 103-115, 2009.
145 Surace, C., Arpicco, S., Dufay-Wojcicki, A., Marsaud, V., Bouclier, C., Clay, D., Cattel, L., Renoir, J.M., Fattal, E., Lipoplexes Targeting the CD44 Hyaluronic Acid Receptor for Efficient Transfection of Breast Cancer Cells. Molecular Pharmaceutics, 6(4), 1062-1073, 2009.
144 Roques, C., Fromes, Y., Fattal, E., Hydrosoluble polymers for muscular gene delivery. European Journal of Pharmaceutics and Biopharmaceutics, 72(2), 378-390, 2009.
143 Roques, C., Fattal, E., Fromes, Y., Comparison of toxicity and transfection efficiency of amphiphilic block copolymers and polycationic polymers in striated muscles. Journal of Gene Medicine, 11(3), 240-249, 2009.
142 Roques, C., Bouchemal, K., Ponchel, G., Fromes, Y., Fattal, E., Parameters affecting organization and transfection efficiency of amphiphilic copolymers/DNA carriers. Journal of Controlled Release, 138(1), 71-77, 2009.
141 Pisani, E., Ringard, C., Nicolas, V., Raphael, E., Rosilio, V., Moine, L., Fattal, E., Tsapis, N., Tuning microcapsules surface morphology using blends of homo- and copolymers of PLGA and PLGA-PEG. Soft Matter, 5(16), 3054-3060, 2009.
140 Khoder, M., Tsapis, N., Huguet, H., Besnard, M., Gueutin, C., Fattal, E., Removal of ciprofloxacin in simulated digestive media by activated charcoal entrapped within zinc-pectinate beads. International Journal of Pharmaceutics, 379(2), 251-259, 2009.
139 Fritsch, P., Serandour, A.L., Gremy, O., Phan, G., Tsapis, N., Abram, M.C., Renault, D., Fattal, E., Benech, H., Deverre, J.R., Poncy, J.L., Simplified Structure of a New Model to Describe Urinary Excretion of Plutonium after Systemic, Liver or Pulmonary Contamination of Rats Associated with Ca-DTPA Treatments. Radiation Research, 171(6), 674-686, 2009.
138 Fritsch, P., Serandour, A.L., Gremy, O., Le Gall, B., Phan, G., Tsapis, N., Fattal, E., Benech, H., Deverre, J.R., Blanchin, N., Grappin, L., Blanchardon, E., Breustedt, B., Poncy, J.L., Modelling Pu/Am decorporation by DTPA. Radioprotection, 44(4), 431-446, 2009.
137 Fattal, E., Barratt, G., Nanotechnologies, and controlled release systems for the delivery of antisense oligonucleotides and small interfering RNA. British Journal of Pharmacology, 157(2), 179-194, 2009.
136 Diaz-Lopez, R., Tsapis, N., Libong, D., Chaminade, P., Connan, C., Chehimi, M.M., Berti, R., Taulier, N., Urbach, W., Nicolas, V., Fattal, E., Phospholipid decoration of microcapsules containing perfluorooctyl bromide used as ultrasound contrast agents. Biomaterials, 30(8), 1462-1472, 2009.
135 Camelo, S., Lajavardi, L., Bochot, A., Goldenberg, B., Naud, M.C., Brunel, N., Lescure, B., Klein, C., Fattal, E., Behar-Cohen, F., de Kozak, Y., Protective Effect of Intravitreal Injection of Vasoactive Intestinal Peptide-Loaded Liposomes on Experimental Autoimmune Uveoretinitis. Journal of Ocular Pharmacology and Therapeutics, 25(1), 9-21, 2009.
134 Bourgeois, S., Tsapis, N., Honnas, H., Andremont, A., Shakweh, M., Besnard, M., Fattal, E., Colonic delivery of beta-lactamases does not affect amoxicillin pharmacokinetics in rats. Journal of Pharmaceutical Sciences, 97(5), 1853-1863, 2008.
133 Gomez Gaete, C., Tsapis, N., Silva, L., Bourgaux, C., Fattal, E., Morphology, structure and supramolecular organization of hybrid 1,2-dipalmitoyl-sn-glycero-3-phosphatidylcholine-hyaluronic acid microparticles prepared by spray drying. European Journal of Pharmaceutical Sciences, 34(1), 12-21, 2008.
132 Fattal, E., Bochot, A., State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers. International Journal of Pharmaceutics, 364(2), 237-248, 2008.
131 Trichard, L., Fattal, E., Le Bas, G., Duchene, D., Grossiord, J.L., Bochot, A., Formulation and characterisation of beads prepared from natural cyclodextrins and vegetable, mineral or synthetic oils. International Journal of Pharmaceutics, 354(1-2), 88-94, 2008.
130 Trichard, L., Delgado-Charro, M.B., Guy, R.H., Fattal, E., Bochot, A., Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug. Pharmaceutical Research, 25(2), 435-440, 2008.
129 Pisani, E., Tsapis, N., Galaz, B., Santin, M., Berti, R., Taulier, N., Kurtisovski, E., Lucidarme, O., Ourevitch, M., Doan, B.T., Beloeil, J.C., Gillet, B., Urbach, W., Bridal, S.L., Fattal, E., Perfluorooctyl Bromide Polymeric Capsules as Dual Contrast Agents for Ultrasonography and Magnetic Resonance Imaging. Advanced Functional Materials, 18(19), 2963-2971, 2008.
128 Pisani, E., Fattal, E., Paris, J., Ringard, C., Rosilio, V., Tsapis, N., Surfactant dependent morphology of polymeric capsules of perfluorooctyl bromide: Influence of polymer adsorption at the dichloromethane-water interface. Journal of Colloid and Interface Science, 326(1), 66-71, 2008.
127 Martini, E., Fattal, E., de Oliveira, M.C., Teixeira, H., Effect of cationic lipid composition on properties of oligonucleotide/emulsion complexes: Physico-chemical and release studies. International Journal of Pharmaceutics, 352(1-2), 280-286, 2008.
126 Gomez-Gaete, C., Tsapis, N., Silva, L., Bourgaux, C., Besnard, M., Bochot, A., Fattal, E., Supramolecular organization, and release properties of phospholipid-hyaluronan microparticles encapsulating dexamethasone. European Journal of Pharmaceutics and Biopharmaceutics, 70(1), 116-126, 2008.
125 Gomez-Gaete, C., Fattal, E., Silva, L., Besnard, M., Tsapis, N., Dexamethasone acetate encapsulation into Trojan particles. Journal of Controlled Release, 128(1), 41-49, 2008.
124 Diaz-Lopez, R., Libong, D., Tsapis, N., Fattal, E., Chaminade, P., Quantification of pegylated phospholipids decorating polymeric microcapsules of perfluorooctyl bromide by reverse phase HPLC with a charged aerosol detector. Journal of Pharmaceutical and Biomedical Analysis, 48(3), 702-707, 2008.
123 De Rosa, G., De Stefano, D., Laguardia, V., Arpicco, S., Simeon, V., Carnuccio, R., Fattal, E., Novel cationic liposome formulation for the delivery of an oligonucleotide decoy to NF-kappa B into activated macrophages. European Journal of Pharmaceutics and Biopharmaceutics, 70(1), 7-18, 2008.
122 Camelo, S., Lajavardi, L., Bochot, A., Goldenberg, B., Naud, M.C., Fattal, E., Behar-Cohen, F., de Kozak, Y., Drainage of fluorescent liposomes from the vitreous to cervical lymph nodes via conjunctival lymphatics. Ophthalmic Research, 40(3-4), 145-150, 2008.
121 Breton, P., Larras, V., Roy, D., Sagodira, S., Limal, D., Bonnafous, D., Colin, N., Bru, N., Fattal, E., Couvreur, P., Biocompatible poly(methylidene malonate)-made materials for pharmaceutical and biomedical applications. European Journal of Pharmaceutics and Biopharmaceutics, 68(3), 479-495, 2008.
120 Bouclier, C., Moine, L., Hillaireau, H., Marsaud, V., Connault, E., Opolon, P., Couvreur, P., Fattal, E., Renoir, J.M., Physicochemical Characteristics and Preliminary in Vivo Biological Evaluation of Nanocapsules Loaded with siRNA Targeting Estrogen Receptor Alpha. Biomacromolecules, 9(10), 2881-2890, 2008.
119 Gomez-Gaete, C., Tsapis, N., Besnard, M., Bochot, A., Fattal, E., Encapsulation of dexamethasone into biodegradable polymeric nanoparticles. International Journal of Pharmaceutics, 331(2), 153-159, 2007.
118 Trichard, L., Fattal, E., Besnard, M., Bochot, A., alpha-Cyclodextrin/oil beads as a new carrier for improving the oral bioavailability of lipophilic drugs. Journal of Controlled Release, 122(1), 47-53, 2007.
117 Serandour, A.L., Tsapis, N., Gervelas, C., Grillon, G., Frechou, M., Deverre, J.R., Benech, H., Fattal, E., Fritsch, P., Poncy, J.L., Decorporation of plutonium by pulmonary administration of Ca-DTPA dry powder: A study in rat after lung contamination with different plutonium forms. Radiation Protection Dosimetry, 127(1-4), 472-476, 2007.
116 Roques, C., Salmon, A., Fiszman, M.Y., Fattal, E., Fromes, Y., Intrapericardial administration of novel DNA formulations based on thermosensitive Poloxamer 407 gel. International Journal of Pharmaceutics, 331(2), 220-223, 2007.
115 Pechine, S., Janoir, C., Boureau, H., Gleizes, A., Tsapis, N., Hoys, S., Fattal, E., Collignon, A., Diminished intestinal colonization by Clostridium difficile and immune response in mice after mucosal immunization with surface proteins of Clostridium difficile. Vaccine, 25(20), 3946-3954, 2007.
114 Lajavardi, L., Bochot, A., Camelo, S., Goldenberg, B., Naud, M.C., Behar-Cohen, F., Fattal, E., de Kozak, Y., Downregulation of endotoxin-induced uveitis by intravitreal injection of vasoactive intestinal peptide encapsulated in liposomes. Investigative Ophthalmology & Visual Science, 48(7), 3230-3238, 2007.
113 Gervelas, C., Serandour, A.L., Geiger, S., Grillon, G., Fritsch, P., Taulelle, C., Le Gall, B., Benech, H., Deverre, J.R., Fattal, E., Tsapis, N., Direct lung delivery of a dry powder formulation of DTPA with improved aerosolization properties: Effect on lung and systemic decorporation of plutonium. Journal of Controlled Release, 118(1), 78-86, 2007.
112 Dribek, M., Le Potier, I., Rodrigues, A., Pallandre, A., Fattal, E., Taverna, M., Determination of binding constants of vasoactive intestinal peptide to poly(amidoamine) dendrimers designed for drug delivery using ACE. Electrophoresis, 28(13), 2191-2200, 2007.
111 Camelo, S., Lajavardi, L., Bochot, A., Goldenberg, B., Naud, M.C., Fattal, E., Behar-Cohen, F., de Kozak, Y., Ocular and systemic bio-distribution of rhodamine-conjugated liposomes loaded with VIP injected into the vitreous of Lewis rats. Molecular Vision, 13(256), 2263-2274, 2007.
110 Bochot, A., Trichard, L., Le Bas, G., Alphandary, H., Grossiord, J.L., Duchene, D., Fattal, E., alpha-Cyclodextrin/oil beads: An innovative self-assembling system. International Journal of Pharmaceutics, 339(1-2), 121-129, 2007.
109 Fattal, E., Bochot, A., Antisense oligonucleotides, aptamers and SiRNA: promises for the treatment of ocular diseases. Archivos de la Sociedad Espanola de Oftalmologia, 81(1), 3-4, 5-6, 2006.
108 Gomes dos Santos, A.L., Bochot, A., Tsapis, N., Artzner, F., Bejjani, R.A., Thillaye-Goldenberg, B., de Kozak, Y., Fattal, E., Behar-Cohen, F., Oligonucleotide-polyethylenimine complexes targeting retinal cells: structural analysis and application to anti-TGFbeta-2 therapy. Pharmaceutical Research, 23(4), 770-781, 2006.
107 Gomes dos Santos, A.L., Bochot, A., Doyle, A., Tsapis, N., Siepmann, J., Siepmann, F., Schmaler, J., Besnard, M., Behar-Cohen, F., Fattal, E., Sustained release of nanosized complexes of polyethylenimine and anti-TGF-beta 2 oligonucleotide improves the outcome of glaucoma surgery. Journal of Controlled Release, 112(3), 369-381, 2006.
106 Toub, N., Malvy, C., Fattal, E., Couvreur, P., Innovative nanotechnologies for the delivery of oligonucleotides and siRNA. Biomedicine & Pharmacotherapy, 60(9), 607-620, 2006.
105 Toub, N., Bertrand, J.R., Tamaddon, A., Elhamess, H., Hillaireau, H., Maksimenko, A., Maccario, J., Malvy, C., Fattal, E., Couvreur, P., Efficacy of siRNA nanocapsules targeted against the EWS-Fli1 oncogene in Ewing sarcoma. Pharmaceutical Research, 23(5), 892-900, 2006.
104 Toub, N., Bertrand, J.R., Malvy, C., Fattal, E., Couvreur, P., Antisense oligonucleotide nanocapsules efficiently inhibit EWS-Fli1 expression in a Ewing’s sarcoma model. Oligonucleotides, 16(2), 158-168, 2006.
103 Shakweh, M., Fattal, E., Design and characterisation of poly(lactide-co-glycolide) small particulate systems for the delivery of immunostimulant CpG oligonucleotide. Journal of Nanoscience and Nanotechnology, 6(9-10), 2811-2820, 2006.
102 Pisani, E., Tsapis, N., Paris, J., Nicolas, V., Cattel, L., Fattal, E., Polymeric nano/microcapsules of liquid perfluorocarbons for ultrasonic imaging: Physical characterization. Langmuir, 22(9), 4397-4402, 2006.
101 Phan, G., Le Gall, B., Grillon, G., Rouit, E., Fouillit, M., Benech, H., Fattal, E., Deverre, J.R., Enhanced decorporation of plutonium by DTPA encapsulated in small PEG-coated liposomes. Biochimie, 88(11), 1843-1849, 2006.
100 Phan, G., Le Gall, B., Deverre, J.R., Fattal, E., Benech, H., Predicting plutonium decorporation efficacy after intravenous administration of DTPA formulations: Study of pharmacokinetic-pharmacodynamic relationships in rats. Pharmaceutical Research, 23(9), 2030-2035, 2006.
99 Maillard, S., Gauduchon, J., Marsaud, V., Gouilleux, F., Connault, E., Opolon, P., Fattal, E., Sola, B., Renoir, J.M., Improved antitumoral properties of pure antiestrogen RU 58668-loaded liposomes in multiple myeloma. Journal of Steroid Biochemistry and Molecular Biology, 100(1-3), 67-78, 2006.
98 Fattal, E., Bochot, A., Ocular delivery of nucleic acids: antisense oligonucleotides, aptamers and siRNA. Advanced Drug Delivery Reviews, 58(11), 1203-1223, 2006.
97 Desire, L., Mysiakine, E., Bonnafous, D., Couvreur, P., Sagodira, S., Breton, P., Fattal, E., Sustained delivery of growth factors from methylidene malonate 2.1.2-based polymers. Biomaterials, 27(12), 2609-2620, 2006.
96 Bourgeois, S., Gernet, M., Pradeau, D., Andremont, A., Fattal, E., Evaluation of critical formulation parameters influencing the bioactivity of beta-lactamases entrapped in pectin beads. International Journal of Pharmaceutics, 324(1), 2-9, 2006.
95 Bourgeois, S., Harvey, R.D., Fattal, E., Polymer colon drug delivery systems and their applications to peptides, proteins, and nucleic acids. American Journal of Drug Delivery, 3(3), 171-204, 2005.
94 Harvey, R.D., Bourgeois, S., Pietzonka, L., Desire, L., Fattal, E., Microencapsulation of nanoparticulate complexes of DNA with cationic lipids and polymers in pectin beads for targeted gene delivery. Nanobiotechnology, 1(1), 71-82, 2005.
93 Gomes Dos Santos, A.L., Bochot, A., Fattal, E., Intraocular delivery of oligonucleotides. Current Pharmaceutical Biotechnology, 6(1), 7-15, 2005.
92 Ungaro, F., De Rosa, G., Quaglia, F., Fattal, E., La Rotonda, M.I., Controlled release of oligonucleotide/polyethyleneimine complexes from PLGA-based microspheres: potential of spray-drying technique. Journal of Drug Delivery Science and Technology, 15(2), 137-143, 2005.
91 Toub, N., Angiari, C., Eboue, D., Fattal, E., Tenu, J.P., Le Doan, T., Couvreur, P., Cellular fate of oligonucleotides when delivered by nanocapsules of poly(isobutylcyanoacrylate). Journal of Controlled Release, 106(1-2), 209-213, 2005.
90 Shakweh, M., Besnard, M., Nicolas, V., Fattal, E., Poly (lactide-co-glycolide) particles of different physicochemical properties and their uptake by Peyer’s patches in mice. European Journal of Pharmaceutics and Biopharmaceutics, 61(1-2), 1-13, 2005.
89 Phan, G., Herbet, A., Cholet, S., Benech, H., Deverre, J.R., Fattal, E., Pharmacokinetics of DTPA entrapped in conventional and long-circulating liposomes of different size for plutonium decorporation. Journal of Controlled Release, 110(1), 177-188, 2005.
88 Maillard, S., Ameller, T., Gauduchon, J., Gougelet, A., Gouilleux, F., Legrand, P., Marsaud, V., Fattal, E., Sola, B., Renoir, J.M., Innovative drug delivery nanosystems improve the anti-tumor activity in vitro and in vivo of anti-estrogens in human breast cancer and multiple myeloma. Journal of Steroid Biochemistry and Molecular Biology, 94(1-3), 111-121, 2005.
87 Maignien, T., Shakweh, M., Calvo, P., Marce, D., Sales, N., Fattal, E., Deslys, J.P., Couvreur, P., Lasmezas, C.I., Role of gut macrophages in mice orally contaminated with scrapie or BSE. International Journal of Pharmaceutics, 298(2), 293-304, 2005.
86 Lavisse, S., Paci, A., Rouffiac, V., Adotevi, C., Opolon, P., Peronneau, P., Bourget, P., Roche, A., Perricaudet, M., Fattal, E., Lassau, N., In vitro echogenicity characterization of poly lactide-coglycolide (PLGA) microparticles and preliminary in vivo ultrasound enhancement study for ultrasound contrast agent application. Investigative Radiology, 40(8), 536-544, 2005.
85 Bourgeois, S., Laham, A., Besnard, M., Andremont, A., Fattal, E., In vitro and in vivo evaluation of pectin beads for the colon delivery of beta-lactamases. Journal of Drug Targeting, 13(5), 277-284, 2005.
84 Boulmedarat, L., Piel, G., Bochot, A., Lesieur, S., Delattre, L., Fattal, E., Cyclodextrin-mediated drug release from liposomes dispersed within a bioadhesive gel. Pharmaceutical Research, 22(6), 962-971, 2005.
83 Boulmedarat, L., Bochot, A., Lesieur, S., Fattal, E., Evaluation of buccal methyl-beta-cyclodextrin toxicity on human oral epithelial cell culture model. Journal of Pharmaceutical Sciences, 94(6), 1300-1309, 2005.
82 Shakweh, M., Ponchel, G., Fattal, E., Particle uptake by Peyer’s patches: a pathway for drug and vaccine delivery. Expert Opinion on Drug Delivery, 1(1), 141-163, 2004.
81 Phan, G., Ramounet-Le Gall, B., Manceau, J., Fanet, M., Benech, H., Fritsch, P., Fattal, E., Deverre, J.R., Targeting of diethylene triamine pentaacetic acid encapsulated in liposomes to rat liver: an effective strategy to prevent bone deposition and increase urine elimination of plutonium in rats. International Journal of Radiation Biology, 80(6), 413-422, 2004.
80 Fattal, E., De Rosa, G., Bochot, A., Gel and solid matrix systems for the controlled delivery of drug carrier-associated nucleic acids. International Journal of Pharmaceutics, 277(1-2), 25-30, 2004.
79 Fattal, E., Couvreur, P., Dubernet, C., “Smart” delivery of antisense oligonucleotides by anionic pH-sensitive liposomes. Advanced Drug Delivery Reviews, 56(7), 931-946, 2004.
78 Quaglia, F., De Rosa, G., Granata, E., Ungaro, F., Fattal, E., Immacolata La Rotonda, M., Feeding liquid, non-ionic surfactant and cyclodextrin affect the properties of insulin-loaded poly(lactide-co-glycolide) microspheres prepared by spray-drying. Journal of Controlled Release, 86(2-3), 267-278, 2003.
77 Maksimenko, A., Lambert, G., Bertrand, J.R., Fattal, E., Couvreur, P., Malvy, C., Therapeutic potentialities of EWS-Fli-1 mRNA-targeted vectorized antisense oligonucleotides. Annals of the New York Academy of Sciences, 100272-77, 2003.
76 Vauthier, C., Dubernet, C., Fattal, E., Pinto-Alphandary, H., Couvreur, P., Poly(alkylcyanoacrylates) as biodegradable materials for biomedical applications. Advanced Drug Delivery Reviews, 55(4), 519-548, 2003.
75 Maksimenko, A., Malvy, C., Lambert, G., Bertrand, J.R., Fattal, E., Maccario, J., Couvreur, P., Oligonucleotides targeted against a junction oncogene are made efficient by nanotechnologies. Pharmaceutical Research, 20(10), 1565-1567, 2003.
74 De Rosa, G., Quaglia, F., Bochot, A., Ungaro, F., Fattal, E., Long-term release and improved intracellular penetration of oligonucleotide-polyethylenimine complexes entrapped in biodegradable microspheres. Biomacromolecules, 4(3), 529-536, 2003.
73 De Rosa, G., Bochot, A., Quaglia, F., Besnard, M., Fattal, E., A new delivery system for antisense therapy: PLGA microspheres encapsulating oligonucleotide/polyethyleneimine solid complexes. International Journal of Pharmaceutics, 254(1), 89-93, 2003.
72 Boulmedarat, L., Grossiord, J.L., Fattal, E., Bochot, A., Influence of methyl-beta-cyclodextrin and liposomes on rheological properties of Carbopol (R) 974P NF gels. International Journal of Pharmaceutics, 254(1), 59-64, 2003.
71 De Rosa, G., Quaglia, F., La Rotonda, M., Besnard, M., Fattal, E., Biodegradable microparticles for the controlled delivery of oligonucleotides. International Journal of Pharmaceutics, 242(1-2), 225-228, 2002.
70 Fattal, E., Pecquet, S., Couvreur, P., Andremont, A., Biodegradable microparticles for the mucosal delivery of antibacterial and dietary antigens. International Journal of Pharmaceutics, 242(1-2), 15-24, 2002.
69 De Rosa, G., Quaglia, F., La Rotonda, M.I., Appel, M., Alphandary, H., Fattal, E., Poly(lactide-co-glycolide) microspheres for the controlled release of oligonucleotide/polyethylenimine complexes. Journal of Pharmaceutical Sciences, 91(3), 790-799, 2002.
68 Couvreur, P., Barratt, G., Fattal, E., Legrand, P., Vauthier, C., Nanocapsule technology: A review. Critical Reviews in Therapeutic Drug Carrier Systems, 19(2), 99-134, 2002.
67 Bochot, A., Fattal, E., Boutet, V., Deverre, J.R., Jeanny, J.C., Chacun, H., Couvreur, P., Intravitreal delivery of oligonucleotides by sterically stabilized liposomes. Investigative Ophthalmology & Visual Science, 43(1), 253-259, 2002.
66 Nicoli, S., Santi, P., Couvreur, P., Couarraze, G., Colombo, P., Fattal, E., Design of triptorelin loaded nanospheres for transdermal iontophoretic administration. International Journal of Pharmaceutics, 214(1-2), 31-35, 2001.
65 Le Visage, C., Quaglia, F., Dreux, M., Ounnar, S., Breton, P., Bru, N., Couvreur, P., Fattal, E., Novel microparticulate system made of poly(methylidene malonate 2.1.2). Biomaterials, 22(16), 2229-2238, 2001.
64 Le Visage, C., Couvreur, P., Passirani, C., Breton, P., Bru, N., Fattal, E., Influence of a non-ionic poloxamer surfactant, Pluronic F68, on protein release from poly(methylidene malonate 2.1.2) microparticles in simulated gastric and intestinal media. STP Pharma Sciences, 11(5), 377-383, 2001.
63 Le Visage, C., Couvreur, P., Mysiakine, E., Breton, P., Bru, N., Fattal, E., In vitro and in vivo evaluation of poly(methylidene malonate 2.1.2) microparticles behavior for oral administration. Journal of Drug Targeting, 9(2), 141-153, 2001.
62 Le Potier, I., Taverna, M., Fattal, E., Benzaki, J., Chevalier, M., Ferrier, D., Performance evaluation of capillary surface treatments for peptide mapping by capillary zone electrophoresis. Chromatographia, 53(9-10), 563-570, 2001.
61 Lambert, G., Fattal, E., Pinto-Alphandary, H., Gulik, A., Couvreur, P., Polyisobutylcyanoacrylate nanocapsules containing an aqueous core for the delivery of oligonucleotides. International Journal of Pharmaceutics, 214(1-2), 13-16, 2001.
60 Lambert, G., Fattal, E., Couvreur, P., Nanoparticulate systems for the delivery of antisense oligonucleotides. Advanced Drug Delivery Reviews, 47(1), 99-112, 2001.
59 Fattal, E., Dubernet, C., Couvreur, P., Liposome-based formulations for the delivery of oligonucleotides. STP Pharma Science, 11(1), 31-44, 2001.
58 De Oliveira, M.C., Dubernet, C., Paternostre, M., Fattal, E., Couvreur, P., Ollivon, M., pH-sensitive liposomes as a carrier for oligonucleotides (ODN): development of a new methodology to follow physicochemical changes along with pH of native and ODN loaded liposomes. STP Pharma Science, 11(1), 103-107, 2001.
57 Calvo, P., Gouritin, B., Chacun, H., Desmaele, D., D’Angelo, J., Noel, J.P., Georgin, D., Fattal, E., Andreux, J.P., Couvreur, P., Long-circulating PEGylated polycyanoacrylate nanoparticles as new drug carrier for brain delivery. Pharmaceutical Research, 18(8), 1157-1166, 2001.
56 Trolle, S., Chachaty, E., Kassis-Chikhani, N., Wang, C., Fattal, E., Couvreur, P., Diamond, B., Alonso, J., Andremont, A., Intranasal immunization with protein-linked phosphorylcholine protects mice against a lethal intranasal challenge with streptococcus pneumoniae. Vaccine, 18(26), 2991-2998, 2000.
55 Pecquet, S., Leo, E., Fritsche, R., Pfeifer, A., Couvreur, P., Fattal, E., Oral tolerance elicited in mice by beta-lactoglobulin entrapped in biodegradable microspheres. Vaccine, 18(13), 1196-1202, 2000.
54 Neveux, N., De Bandt, J.P., Fattal, E., Hannoun, L., Poupon, R., Chaumeil, J.C., Delattre, J., Cynober, L.A., Cold preservation injury in rat liver: effect of liposomally-entrapped adenosine triphosphate. Journal of Hepatology, 33(1), 68-75, 2000.
53 Lambert, G., Fattal, E., Pinto-Alphandary, H., Gulik, A., Couvreur, P., Polyisobutylcyanoacrylate nanocapsules containing an aqueous core as a novel colloidal carrier for the delivery of oligonucleotides. Pharmaceutical Research, 17(6), 707-714, 2000.
52 Lambert, G., Bertrand, J.R., Fattal, E., Subra, F., Pinto-Alphandary, H., Malvy, C., Auclair, C., Couvreur, P., EWS Fli-1 antisense nanocapsules inhibits Ewing sarcoma-related tumor in mice. Biochemical and Biophysical Research Communications, 279(2), 401-406, 2000.
51 De Oliveira, M.C., Boutet, V., Fattal, E., Boquet, D., Grognet, J.M., Couvreur, P., Deverre, J.R., Improvement of in vivo stability of phosphodiester oligonucleotide using anionic liposomes in mice. Life Sciences, 67(13), 1625-1637, 2000.
50 Bochot, A., Couvreur, P., Fattal, E., Intravitreal administration of antisense oligonucleotides: Potential of liposomal delivery. Progress in Retinal and Eye Research, 19(2), 131-147, 2000.
49 Trolle, S., Caudron, E., Leo, E., Couvreur, P., Andremont, A., Fattal, E., In vivo fate and immune pulmonary response after nasal administration of microspheres loaded with phosphorylcholine-thyroglobulin. International Journal of Pharmaceutics, 183(1), 73-79, 1999.
48 Rojas, J., Pinto-Alphandary, H., Leo, E., Pecquet, S., Couvreur, P., Gulik, A., Fattal, E., A polysorbate-based non-ionic surfactant can modulate loading and release of beta-lactoglobulin entrapped in multiphase poly(DL-lactide-co-glycolide) microspheres. Pharmaceutical Research, 16(2), 255-260, 1999.
47 Rojas, J., Pinto-Alphandary, H., Leo, E., Pecquet, S., Couvreur, P., Fattal, E., Optimization of the encapsulation and release of beta-lactoglobulin entrapped poly(DL-lactide-co-glycolide) microspheres. International Journal of Pharmaceutics, 183(1), 67-71, 1999.
46 Peracchia, M.T., Fattal, E., Desmaele, D., Besnard, M., Noel, J.P., Gomis, J.M., Appel, M., d’Angelo, J., Couvreur, P., Stealth (R) PEGylated polycyanoacrylate nanoparticles for intravenous administration and splenic targeting. Journal of Controlled Release, 60(1), 121-128, 1999.
45 Fattal, E., Delattre, J., Dubernet, C., Couvreur, P., Liposomes for the delivery of nucleotides and oligonucleotides. STP Pharma Science, 9(5), 383-390, 1999.
44 Aynie, I., Vauthier, C., Chacun, H., Fattal, E., Couvreur, P., Spongelike alginate nanoparticles as a new potential system for the delivery of antisense oligonucleotides. Antisense & Nucleic Acid Drug Development, 9(3), 301-312, 1999.
43 Trolle, S., Andremont, A., Fattal, E., Towards a multipurpose mucosal vaccination using phosphorylcholine as a unique antigen? STP Pharma Sciences, 8(1), 19-30, 1998.
42 Skiba-Lahiani, M., Skiba, M., Nikas, G., Auger, J., Fattal, E., Delattre, J., Courtot, A.M., Interaction between PC12 liposomes encapsulating ATP and human spermatozoa. International Journal of Pharmaceutics, 172(1-2), 147-159, 1998.
41 Leo, E., Pecquet, S., Rojas, J., Couvreur, P., Fattal, E., Changing the pH of the external aqueous phase may modulate protein entrapment and delivery from poly(lactide-co-glycolide) microspheres prepared by a w/o/w solvent evaporation method. Journal of Microencapsulation, 15(4), 421-430, 1998.
40 Lambert, G., Fattal, E., Brehier, A., Feger, J., Couvreur, P., Effect of polyisobutylcyanoacrylate nanoparticles and Lipofectin (R) loaded with oligonucleotides on cell viability and PKC alpha neosynthesis in HepG2 cells. Biochimie, 80(12), 969-976, 1998.
39 Fattal, E., Vauthier, C., Aynie, I., Nakada, Y., Lambert, G., Malvy, C., Couvreur, P., Biodegradable polyalkylcyanoacrylate nanoparticles for the delivery of oligonucleotides. Journal of Controlled Release, 53(1-3), 137-143, 1998.
38 De Oliveira, M.C., Fattal, E., Couvreur, P., Lesieur, P., Bourgaux, C., Ollivon, M., Dubernet, C., pH-Sensitive liposomes as a carrier for oligonucleotides: a physico-chemical study of the interaction between DOPE and a 15-mer oligonucleotide in quasi-anhydrous samples. Biochimica et Biophysica Acta-Biomembranes, 1372(2), 301-310, 1998.
37 Bochot, A., Mashhour, B., Puisieux, F., Couvreur, P., Fattal, E., Comparison of the ocular distribution of a model oligonucleotide after topical instillation in rabbits of conventional and new dosage forms. Journal of Drug Targeting, 6(4), 309-313, 1998.
36 Bochot, A., Fattal, E., Gulik, A., Couarraze, G., Couvreur, P., Liposomes dispersed within a thermosensitive gel: A new dosage form for ocular delivery of oligonucleotides. Pharmaceutical Research, 15(9), 1364-1369, 1998.
35 Bochot, A., Fattal, E., Grossiord, J.L., Puisieux, F., Couvreur, P., Characterization of a new ocular delivery system based on a dispersion of liposomes in a thermosensitive gel. International Journal of Pharmaceutics, 162(1-2), 119-127, 1998.
34 Allaoui-Attarki, K., Fattal, E., Pecquet, S., Trolle, S., Chachaty, E., Couvreur, P., Andremont, A., Mucosal immunogenicity elicited in mice by oral vaccination with phosphorylcholine encapsulated in poly (D,L-lactide-co-glycolide) microspheres. Vaccine, 16(7), 685-691, 1998.
33 Couvreur, P., Fattal, E., Malvy, C., Dubernet, C., pH-sensitive liposomes: an intelligent system for the delivery of antisense oligonucleotides. Journal of Liposome Research, 7(1), 1-18, 1997.
32 Fernandez-Urrusuno, R., Fattal, E., Feger, J., Couvreur, P., Therond, P., Evaluation of hepatic antioxidant systems after intravenous administration of polymeric nanoparticles. Biomaterials, 18(6), 511-517, 1997.
31 Quintilio, W., Sato, R.A., Da Silveira, A.M., Barratt, G., Fattal, E., BuenodaCosta, M.H., Microquantification of proteins with low chromophore content. Biotechnology Techniques, 11(9), 697-700, 1997.
30 De Oliveira, M.C., Fattal, E., Ropert, C., Malvy, C., Couvreur, P., Delivery of antisense oligonucleotides by means of pH-sensitive liposomes. Journal of Controlled Release, 48(2-3), 179-184, 1997.
29 Couvreur, P., BlancoPrieto, M.J., Puisieux, F., Roques, B., Fattal, E., Multiple emulsion technology for the design of microspheres containing peptides and oligopeptides. Advanced Drug Delivery Reviews, 28(1), 85-96, 1997.
28 Blanco-Prieto, M.J., Fattal, E., Gulik, A., Dedieu, J.C., Roques, B.P., Couvreur, P., Characterization and morphological analysis of a cholecystokinin derivative peptide-loaded poly(lactide-co-glycolide) microspheres prepared by a water-in-oil-in-water emulsion solvent evaporation method. Journal of Controlled Release, 43(1), 81-87, 1997.
27 Allaoui-Attarki, K., Pecquet, S., Fattal, E., Trolle, S., Chachaty, E., Couvreur, P., Andremont, A., Protective immunity against Salmonella typhimurium elicited in mice by oral vaccination with phosphorylcholine encapsulated in poly(DL-lactide-co-glycolide) microspheres. Infection and Immunity, 65(3), 853-857, 1997.
26 Brazeau, G.A., Sciame, M., al-Suwayeh, S.A., Fattal, E., Evaluation of PLGA microsphere size effect on myotoxicity using the isolated rodent skeletal muscle model. Pharmaceutical Development and Technology, 1(3), 279-283, 1996.
25 Ramaldes, G.A., Fattal, E., Puisieux, F., Ollivon, M., Solubilization kinetics of phospholipid vesicles by sodium taurocholate. Colloids and Surfaces B-Biointerfaces, 6(6), 363-371, 1996.
24 Ramaldes, G.A., Deverre, J.R., Grognet, J.M., Puisieux, F., Fattal, E., Use of an enzyme immunoassay for the evaluation of entrapment efficiency and in vitro stability in intestinal fluids of liposomal bovine serum albumin. International Journal of Pharmaceutics, 143(1), 1-11, 1996.
23 Nakada, Y., Fattal, E., Foulquier, M., Couvreur, P., Pharmacokinetics and biodistribution of oligonucleotide adsorbed onto poly(isobutylcyanoacrylate) nanoparticles after intravenous administration in mice. Pharmaceutical Research, 13(1), 38-43, 1996.
22 Fernandez-Urrusuno, R., Fattal, E., Rodrigues, J.M., Feger, J., Bedossa, P., Couvreur, P., Effect of polymeric nanoparticle administration on the clearance activity of the mononuclear phagocyte system in mice. Journal of Biomedical Materials Research, 31(3), 401-408, 1996.
21 Blanco-Prieto, M.J., Leo, E., Delie, F., Gulik, A., Couvreur, P., Fattal, E., Study of the influence of several stabilizing agents on the entrapment and in vitro release of pBC 264 from poly(lactide-co-glycolide) microspheres prepared by a W/O/W solvent evaporation method. Pharmaceutical Research, 13(7), 1127-1129, 1996.
20 Blanco-Prieto, M.J., Durieux, C., Dauge, V., Fattal, E., Couvreur, P., Roques, B.P., Slow delivery of the selective cholecystokinin agonist pBC 264 into the rat nucleus accumbens using microspheres. Journal of Neurochemistry, 67(6), 2417-2424, 1996.
19 Aynie, I., Vauthier, C., Foulquier, M., Malvy, C., Fattal, E., Couvreur, P., Development of a quantitative polyacrylamide gel electrophoresis analysis using a multichannel radioactivity counter for the evaluation of oligonucleotide-bound drug carrier. Analytical Biochemistry, 240(2), 202-209, 1996.
18 Fernandez-Urrusuno, R., Fattal, E., Porquet, D., Feger, J., Couvreur, P., Evaluation of liver toxicological effects induced by polyalkylcyanoacrylate nanoparticles. Toxicology and Applied Pharmacology, 130(2), 272-279, 1995.
17 Fernandez-Urrusuno, R., Fattal, E., Porquet, D., Feger, J., Couvreur, P., Influence of surface properties on the inflammatory response to polymeric nanoparticles. Pharmaceutical Research, 12(9), 1385-1387, 1995.
16 Skiba-Lahiani, M., Auger, J., Terribile, J., Fattal, E., Delattre, J., Puisieux, F., Jouannet, P., Stimulation of movement and acrosome reaction of human spermatozoa by PC12 liposomes encapsulating ATP. International Journal of Andrology, 18(6), 287-294, 1995.
15 Puisieux, F., Fattal, E., Lahiani, M., Auger, J., Jouannet, P., Couvreur, P., Delattre, J., Liposomes, an interesting tool to deliver a bioenergetic substrate (ATP). in vitro and in vivo studies. Journal of Drug Targeting, 2(5), 443-448, 1994.
14 Fattal, E., Nir, S., Parente, R.A., Szoka, F.C., Jr., Pore-forming peptides induce rapid phospholipid flip-flop in membranes. Biochemistry, 33(21), 6721-6731, 1994.
13 Blanco-Prieto, M.J., Delie, F., Fattal, E., Tartar, A., Puisieux, F., Gulik, A., Couvreur, P., Characterization of V3 BRU peptide-loaded small PLGA microspheres prepared by a (W(1)/O)W(2) emulsion solvent evaporation method. International Journal of Pharmaceutics, 111(2), 137-145, 1994.
12 Maaßen, S., Fattal, E., Muller, R.H., Couvreur, P., Cell cultures for the assessment of toxicity and uptake of polymeric particulate drug carriers. STP Pharma Science, 3(1), 11-22, 1993.
11 Puisieux, F., Fattal, E., Couvreur, P., Rossignol, P., Delattre, J., Liposomes their fate in-vivo and their possible therapeutic use (iv route) – efficiency of liposome-entrapped ATP in cerebral-ischemia. Phosphorus Sulfur and Silicon and the Related Elements, 77(1-4), 661-664, 1993.
10 Couvreur, P., Fattal, E., Alphandary, H.P., F., Andremont, A., Intracelllular targeting of antibiotics by means of biodegradable nanoparticles. Journal of Controlled Release, 19F259-268, 1992.
9 Fattal, E., Rojas, J., Roblot-Treupel, L., Andremont, A., Couvreur, P., Ampicillin-loaded liposomes and nanoparticles: comparison of drug loading, drug release and in vitro antimicrobial activity. Journal of Microencapsulation, 8(1), 29-36, 1991.
8 Fattal, E., Rojas, J., Youssef, M., Couvreur, P., Andremont, A., Liposome-entrapped ampicillin in the treatment of experimental murine listeriosis and salmonellosis. Antimicrobial Agents and Chemotherapy, 35(4), 770-772, 1991.
7 Couvreur, P., Fattal, E., Andremont, A., Liposomes and nanoparticles in the treatment of intracellular bacterial infections. Pharmaceutical Research, 8(9), 1079-1086, 1991.
6 Seijo, B., Fattal, E., Roblot-Treupel, L., Couvreur, P., Design of nanoparticles sizing less than 50 nm: preparation, characterization and drug loading. International Journal of Pharmaceutics, 62(1), 1-7, 1990.
5 Fattal, E., Youssef, M., Couvreur, P., Andremont, A., Treatment of experimental salmonellosis in mice with ampicillin-bound nanoparticles. Antimicrobial Agents and Chemotherapy, 33(9), 1540-1543, 1989.
4 Laham, A., Claperon, N., Durussel, J.J., Fattal, E., Delattre, J., Puisieux, F., Couvreur, P., Rossignol, P., Liposomally entrapped adenosine triphosphate. Improved efficiency against experimental brain ischaemia in the rat. Journal of Chromatography, 440455-458, 1988.
3 Youssef, M., Fattal, E., Alonso, M.J., Roblot-Treupel, L., Sauzieres, J., Tancrede, C., Omnes, A., Couvreur, P., Andremont, A., Effectiveness of nanoparticle-bound ampicillin in the treatment of Listeria monocytogenes infection in athymic nude mice. Antimicrobial Agents and Chemotherapy, 32(8), 1204-1207, 1988.
2 Laham, A., Claperon, N., Durussel, J.J., Fattal, E., Delattre, J., Puisieux, F., Couvreur, P., Rossignol, P., Intracarotidal administration of liposomally-entrapped ATP: improved efficiency against experimental brain ischemia. Pharmacological Research Communications, 20(8), 699-705, 1988.
1 Laham, A., Claperon, N., Durussel, J.J., Fattal, E., Delattre, J., Puisieux, F., Couvreur, P., Rossignol, P., Liposomally-entrapped ATP: improved efficiency against experimental brain ischemia in the rat. Life Sciences, 40(20), 2011-2016, 1987.
